With a very small quantity of active pharmaceutical ingredients (API) or druggable candidate molecules, Medicilon’s pre-formulation service can provide valuable information and expertise to guide the compounds to next steps. Our pre-formulation team has extensive experience on handling a wide range of compounds and we can suggest the path forward for early success.
Preclinical Candidate Characterization
pH solubility profile
Solubility in organic solvents
Solubility in Fasted State Simulated Intestinal Fluid (FaSSIF), Fed State Simulated Intestinal Fluid (FeSSIF) and Simulated Gastric Fluid (SGF)
Solution stability, solid state stability, ICH photostability