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현재 위치: > Services & Solutions > Drug Formulation > Pre-Formulation Deve...

With a very small quantity of active pharmaceutical ingredients (API) or druggable candidate molecules, Medicilon’s pre-formulation service can provide valuable information and expertise to guide the compounds to next steps. Our pre-formulation team has extensive experience on handling a wide range of compounds and we can suggest the path forward for early success.

Preclinical Candidate Characterization金沙2015手机版下载

Solubility:
  • pH solubility profile
  • Solubility in organic solvents
  • Solubility in Fasted State Simulated Intestinal Fluid (FaSSIF), Fed State Simulated Intestinal Fluid (FeSSIF) and Simulated Gastric Fluid (SGF)
Stability:
  • Solution stability, solid state stability, ICH photostability
Inherent Properties:
  • pKa, Log p/Log D, Intrinsic dissolution, etc.

Enabling Formulation Development for Screening

  • Vehicle selection
  • pH adjustment and co-solvent
  • Surfactant solubilization
  • Nanosuspension
  • Microemulsion
  • Amorphous solid dispersion

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